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39 However, in OA cartilage, various matrix-degrading enzymes, including MMP-3, MMP-9, and ADAMTS-4, are markedly elevated and are associated with promoter demethylation events

Copper is required for activity at the cellular receptor level, and the copper ion is what makes the molecule a meaningful regulator of matrix metalloproteinases and their tissue inhibitors 2

Some products and articles confuse the seven-residue fragment with full thymosin beta-4

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